RAD54B, RAD54 homolog B

RAD54B, RAD54 homolog B

• The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer. [provided by RefSeq, Jul 2008]

• Gene Synonyms (DNA repair and recombination protein RAD54B, RDH54,)
• NCBI Gene ID: 25788
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y620
  UNIPROT ID#>>A0A087X0H2
  UNIPROT ID#>>O95073
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

RAD54 homolog B interacts with:

• ATP synthase mitochondrial F1 complex assembly factor 2
  coiled-coil domain containing 33
  copine 5
  egl-9 family hypoxia inducible factor 3
  enkurin domain containing 1
  germ cell-less 1, spermatogenesis associated
  golgi reassembly stacking protein 2
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  ligand of numb-protein X 1
  MAF1 homolog, negative regulator of RNA polymerase III
  myosin XVB
  NGG1 interacting factor 3 like 1
  nudix hydrolase 18
  RAD54 homolog B
  RIB43A domain with coiled-coils 2
  trafficking protein particle complex 6A
  transcription elongation factor A N-terminal and central domain containing
  zinc finger protein 580

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.