ZEB2, zinc finger E-box binding homeobox 2

ZEB2, zinc finger E-box binding homeobox 2

• The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]

• Gene Synonyms (zinc finger E-box-binding homeobox 2, SMAD interacting protein 1, Smad-interacting protein 1, zinc finger homeobox 1b, HSPC082, SIP-1, SIP1, SMADIP1, ZFHX1B,)
• NCBI Gene ID: 9839
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O60315
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

zinc finger E-box binding homeobox 2 interacts with:

• COP9 signalosome subunit 6
  F-box and WD repeat domain containing 7
  F-box protein 38
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.