ARHGAP32, Rho GTPase activating protein 32

ARHGAP32, Rho GTPase activating protein 32

• RICS is a neuron-associated GTPase-activating protein that may regulate dendritic spine morphology and strength by modulating Rho GTPase (see RHOA; MIM 165390) activity (Okabe et al., 2003 [PubMed 12531901]).[supplied by OMIM, Mar 2008]

• Gene Synonyms (rho GTPase-activating protein 32, GAB-associated CDC42, GAB-associated Cdc42/Rac GTPase-activating protein, GTPase regulator interacting with TrkA, GTPase-activating protein for Cdc42 and Rac1, RhoGAP involved in the -catenin-N-cadherin and NMDA receptor signaling, brain-specific Rho GTP-ase-activating protein, brain-specific Rho GTPase-activating protein, rac GTPase activating protein, rho-type GTPase-activating protein 32, rho/Cdc42/Rac GTPase-activating protein RICS, rhoGAP involved in the beta-catenin-N-cadherin and NMDA receptor signaling, GC-GAP, GRIT, PX-RICS, RICS, p200RhoGAP, p250GAP,)
• NCBI Gene ID: 9743
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A7KAX9
  UNIPROT ID#>>Q86T64
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Rho GTPase activating protein 32 interacts with:

• abl interactor 2
  ankyrin repeat and SOCS box containing 3
  calcium/calmodulin dependent protein kinase II inhibitor 2
  chaperonin containing Tcp1, subunit 4 (delta)
  cullin 7
  egl-9 family hypoxia inducible factor 3
  fizzy and cell division cycle 20 related 1
  GRB2 associated binding protein 2
  GRB2 related adaptor protein
  leucine zipper tumor suppressor 2
  MAD2L1 binding protein
  multiple EGF like domains 10
  nuclear RNA export factor 1
  obscurin like cytoskeletal adaptor 1
  SHC adaptor protein 2
  SHC adaptor protein 3
  SMAD specific E3 ubiquitin protein ligase 1
  small glutamine rich tetratricopeptide repeat containing beta
  synaptotagmin binding cytoplasmic RNA interacting protein
  vir like m6A methyltransferase associated
  ZW10 interacting kinetochore protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.