ROCK2, Rho associated coiled-coil containing protein kinase 2

ROCK2, Rho associated coiled-coil containing protein kinase 2

• The protein encoded by this gene is a serine/threonine kinase that regulates cytokinesis, smooth muscle contraction, the formation of actin stress fibers and focal adhesions, and the activation of the c-fos serum response element. This protein, which is an isozyme of ROCK1 is a target for the small GTPase Rho. [provided by RefSeq, Jul 2008]

• Gene Synonyms (rho-associated protein kinase 2, p164 ROCK-2, rho-associated, coiled-coil-containing protein kinase II, ROCK-II,)
• NCBI Gene ID: 9475
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14DU5
  UNIPROT ID#>>O75116
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Rho associated coiled-coil containing protein kinase 2 interacts with:

• DDB1 and CUL4 associated factor 15
  DnaJ heat shock protein family (Hsp40) member B11
  F-box protein 42
  gephyrin
  inhibitor of nuclear factor kappa B kinase subunit epsilon
  leucine zipper transcription factor like 1
  MAGE family member C1
  magnesium dependent phosphatase 1
  pleckstrin homology domain containing A4
  RAB guanine nucleotide exchange factor 1
  Rac GTPase activating protein 1
  Rho related BTB domain containing 1
  Rho-associated coiled-coil containing protein kinase 1
  RNA polymerase I and III subunit C
  SNW domain containing 1
  vir like m6A methyltransferase associated
  WASH complex subunit 2A
  WASH complex subunit 5

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.