TGM5, transglutaminase 5

TGM5, transglutaminase 5

• This gene encodes a member of the transglutaminase family. The encoded protein catalyzes formation of protein cross-links between glutamine and lysine residues, often resulting in stabilization of protein assemblies. This reaction is calcium dependent. Mutations in this gene have been associated with acral peeling skin syndrome. [provided by RefSeq, Oct 2009]

• Gene Synonyms (protein-glutamine gamma-glutamyltransferase 5, TG(X), TGase X, TGase-5, transglutaminase V, transglutaminase X, PSS2, TGASE5, TGASEX, TGM6, TGMX, TGX,)
• NCBI Gene ID: 9333
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B4DPS8
  UNIPROT ID#>>O43548
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

transglutaminase 5 interacts with:

• coiled-coil domain containing 51
  dedicator of cytokinesis 7
  eukaryotic translation initiation factor 4E family member 2
  galectin 7B
  integrator complex subunit 14
  KN motif and ankyrin repeat domains 2
  La ribonucleoprotein 4
  NHL repeat containing 2
  PDZ domain containing 11
  raftlin, lipid raft linker 1
  RNA binding motif protein 41
  RNA polymerase I subunit F
  spindle and centriole associated protein 1
  zinc finger HIT-type containing 6

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.