S1PR2, sphingosine-1-phosphate receptor 2

S1PR2, sphingosine-1-phosphate receptor 2

• This gene encodes a member of the G protein-coupled receptors, as well as the EDG family of proteins. The encoded protein is a receptor for sphingosine 1-phosphate, which participates in cell proliferation, survival, and transcriptional activation. Defects in this gene have been associated with congenital profound deafness. [provided by RefSeq, Mar 2016]

• Gene Synonyms (sphingosine 1-phosphate receptor 2, CTD-2369P2.2, S1P receptor 2, S1P receptor EDG5, S1P receptor Edg-5, deafness, autosomal recessive 68, endothelial differentiation G-protein coupled receptor 5, endothelial differentiation, sphingolipid G-protein-coupled receptor, 5, sphingosine 1-phosphate receptor Edg-5, AGR16, DFNB68, EDG-5, EDG5, Gpcr13, H218, LPB2, S1P2,)
• NCBI Gene ID: 9294
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R7B2
  UNIPROT ID#>>O95136
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sphingosine-1-phosphate receptor 2 interacts with:

• ADP ribosylation factor like GTPase 6 interacting protein 5
  FKBP prolyl isomerase 14
  G protein subunit alpha 13
  N-myc downstream regulated 1
  paralemmin 3
  phosphoprotein membrane anchor with glycosphingolipid microdomains 1
  phosphotriesterase related
  protein O-mannose kinase
  receptor accessory protein 6
  SHANK associated RH domain interactor
  WD repeat and FYVE domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.