CABLES1, Cdk5 and Abl enzyme substrate 1

CABLES1, Cdk5 and Abl enzyme substrate 1

• This gene encodes a protein involved in regulation of the cell cycle through interactions with several cyclin-dependent kinases. One study (PMID: 16177568) reported aberrant splicing of transcripts from this gene which results in removal of the cyclin binding domain only in human cancer cells, and reduction in gene expression was shown in colorectal cancers (PMID: 17982127).Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]

• Gene Synonyms (CDK5 and ABL1 enzyme substrate 1, interactor with CDK3 1, CABL1, CABLES, HsT2563, IK3-1,)
• NCBI Gene ID: 91768
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8TDN4
  UNIPROT ID#>>A7K6Y5
  UNIPROT ID#>>A0A024RC20
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Cdk5 and Abl enzyme substrate 1 interacts with:

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.