- Gene Overview
- Interaction Network
- Sequence Verification
WFDC8, WAP four-disulfide core domain 8
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This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. The encoded protein contains a Kunitz-inhibitor domain, in addition to three WFDC domains. Most WFDC genes are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode the same protein. [provided by RefSeq, Jul 2008]
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Gene Synonyms (WAP four-disulfide core domain protein 8, WAP motif protein 1, epididymis secretory protein Li 292, epididymis secretory sperm binding protein, protease inhibitor WAP8, putative protease inhibitor WAP8, testicular secretory protein Li 68, C20orf170, HEL-S-292, WAP8, dJ461P17.1,)
- NCBI Gene ID:
90199
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>A0A140VK68
UNIPROT ID#>>Q8IUA0
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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WAP four-disulfide core domain 8 interacts with:
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