- Gene Overview
- Interaction Network
- Sequence Verification
H2AC12, H2A clustered histone 12
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H2A family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the histone microcluster on chromosome 6p21.33. [provided by RefSeq, Aug 2015]
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Gene Synonyms (histone H2A type 1-H, H2A histone family member, histone H2A/s, histone cluster 1 H2A family member h, histone cluster 1, H2ah, H2A/S, H2AFALii, H2AH, HIST1H2AH, dJ86C11.1,)
- NCBI Gene ID:
85235
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>A3KPC7
UNIPROT ID#>>Q96KK5
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
H2A clustered histone 12 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
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