GFM2, GTP dependent ribosome recycling factor mitochondrial 2

GFM2, GTP dependent ribosome recycling factor mitochondrial 2

• Eukaryotes contain two protein translational systems, one in the cytoplasm and one in the mitochondria. Mitochondrial translation is crucial for maintaining mitochondrial function and mutations in this system lead to a breakdown in the respiratory chain-oxidative phosphorylation system and to impaired maintenance of mitochondrial DNA. This gene encodes one of the mitochondrial translation elongation factors, which is a GTPase that plays a role at the termination of mitochondrial translation by mediating the disassembly of ribosomes from messenger RNA . Its role in the regulation of normal mitochondrial function and in disease states attributed to mitochondrial dysfunction is not known. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2013]

• Gene Synonyms (ribosome-releasing factor 2, mitochondrial, G elongation factor mitochondrial 2, mitochondrial elongation factor G2, mitochondrial ribosome recycling factor 2, mitochondrial ribosome-releasing factor 2, ribosome releasing factor 2, EF-G2mt, EFG2, MRRF2, MST027, MSTP027, RRF, RRF2, RRF2mt, hEFG2, mEF-G 2,)
• NCBI Gene ID: 84340
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RAK1
  UNIPROT ID#>>Q969S9
  UNIPROT ID#>>A0A024RAJ7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

GTP dependent ribosome recycling factor mitochondrial 2 interacts with:

• NADH:ubiquinone oxidoreductase core subunit S7
  pregnancy specific beta-1-glycoprotein 8
  tripartite motif containing 41
  tripartite motif containing 9

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.