LOXL4, lysyl oxidase like 4

LOXL4, lysyl oxidase like 4

• This gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family. [provided by RefSeq, Jul 2008]

• Gene Synonyms (lysyl oxidase homolog 4, lysyl oxidase related C, lysyl oxidase-like 4 pseudogene, lysyl oxidase-like protein 4, lysyl oxidase-related protein C, LOXC,)
• NCBI Gene ID: 84171
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96JB6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

lysyl oxidase like 4 interacts with:

• metadherin
  ring finger protein 32

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.