ARID5B, AT-rich interaction domain 5B

ARID5B, AT-rich interaction domain 5B

• This gene encodes a member of the AT-rich interaction domain (ARID) family of DNA binding proteins. The encoded protein forms a histone H3K9Me2 demethylase complex with PHD finger protein 2 and regulates the transcription of target genes involved in adipogenesis and liver development. This gene also plays a role in cell growth and differentiation of B-lymphocyte progenitors, and single nucleotide polymorphisms in this gene are associated with acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Sep 2011]

• Gene Synonyms (AT-rich interactive domain-containing protein 5B, ARID domain-containing protein 5B, AT-rich interactive domain 5B (MRF1-like), MRF1-like protein, modulator recognition factor 2 (MRF2), DESRT, MRF-2, MRF2,)
• NCBI Gene ID: 84159
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q14865
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

AT-rich interaction domain 5B interacts with:

• chromosome 16 open reading frame 87
  egl-9 family hypoxia inducible factor 3
  H2B clustered histone 1
  zinc finger and BTB domain containing 38

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.