QTRT1, queuine tRNA-ribosyltransferase catalytic subunit 1

QTRT1, queuine tRNA-ribosyltransferase catalytic subunit 1

• This gene encodes the catalytic subunit of tRNA-guanine transglycosylase. tRNA-guanine transglycosylase is a heterodimeric enzyme complex that plays a critical role in tRNA modification by synthesizing the 7-deazaguanosine queuosine, which is found in tRNAs that code for asparagine, aspartic acid, histidine and tyrosine. A pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Feb 2012]

• Gene Synonyms (queuine tRNA-ribosyltransferase catalytic subunit 1, TGT, 43-KD subunit, TGT, catalytic subunit, guanine insertion enzyme, queuine tRNA-ribosyltransferase 1, tRNA-guanine transglycosylase, FP3235, TGT, TGUT,)
• NCBI Gene ID: 81890
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BXR0
  UNIPROT ID#>>Q71RF8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

queuine tRNA-ribosyltransferase catalytic subunit 1 interacts with:

• DDB1 and CUL4 associated factor 15

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.