AKAP1, A-kinase anchoring protein 1

AKAP1, A-kinase anchoring protein 1

• The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment. [provided by RefSeq, Jul 2008]

• Gene Synonyms (A-kinase anchor protein 1, mitochondrial, A kinase (PRKA) anchor protein 1, A-kinase anchor protein 149 kDa, AKAP 149, D-AKAP-1, dual-specificity A-kinase anchoring protein 1, protein kinase A anchoring protein 1, protein kinase A1, protein phosphatase 1, regulatory subunit 43, spermatid A-kinase anchor protein 84, testicular secretory protein Li 5, tudor domain containing 17, AKAP, AKAP121, AKAP149, AKAP84, D-AKAP1, PPP1R43, PRKA1, SAKAP84, TDRD17,)
• NCBI Gene ID: 8165
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q92667
  UNIPROT ID#>>A0A140VK05
  UNIPROT ID#>>B4DN86
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

A-kinase anchoring protein 1 interacts with:

• apoptosis inducing factor mitochondria associated 1
  centrosomal protein 43
  cilia and flagella associated protein 91
  cytochrome c oxidase assembly factor COX14
  cytoskeleton associated protein 5
  egl-9 family hypoxia inducible factor 3
  FERM, ARH/RhoGEF and pleckstrin domain protein 1
  hypoxia inducible factor 1 subunit alpha inhibitor
  La ribonucleoprotein 4
  MYC binding protein
  peptidyl-tRNA hydrolase 2
  plasminogen receptor with a C-terminal lysine
  pleckstrin homology domain containing A4
  prohibitin 2
  protein kinase, cAMP dependent regulatory, type II alpha
  protein kinase, cAMP dependent, catalytic, beta
  protein tyrosine phosphatase non-receptor type 21
  PYM homolog 1, exon junction complex associated factor
  regulation of nuclear pre-mRNA domain containing 1B
  ribonuclease P and MRP subunit p25
  serine protease 37
  sideroflexin 1
  translocase of outer mitochondrial membrane 20
  translocase of outer mitochondrial membrane 22
  transmembrane protein 67
  ZFP41 zinc finger protein

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.