APOL3, apolipoprotein L3

APOL3, apolipoprotein L3

• This gene is a member of the apolipoprotein L gene family, and it is present in a cluster with other family members on chromosome 22. The encoded protein is found in the cytoplasm, where it may affect the movement of lipids, including cholesterol, and/or allow the binding of lipids to organelles. In addition, expression of this gene is up-regulated by tumor necrosis factor-alpha in endothelial cells lining the normal and atherosclerotic iliac artery and aorta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]

• Gene Synonyms (apolipoprotein L3, TNF-inducible protein CG12-1, apolipoprotein L, 3, apolipoprotein L-III, apolipoprotein L-III splice variant alpha, apolipoprotein L-III splice variant beta, APOLIII, CG121, CG12_1, apoL-III,)
• NCBI Gene ID: 80833
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O95236
  UNIPROT ID#>>A0A024R1G6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

apolipoprotein L3 interacts with:

• fetal and adult testis expressed 1
  FXYD6-FXYD2 readthrough
  G protein-coupled receptor 152
  leucine rich repeat containing 25
  LHFPL tetraspan subfamily member 5
  neurocalcin delta
  ring finger protein 19B
  transmembrane protein 52B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.