ESX1, ESX homeobox 1

ESX1, ESX homeobox 1

• This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain. The C-terminal fragment localizes to the cytoplasm while the N-terminal fragment localizes exclusively to the nucleus. In contrast to human, the mouse homolog has a novel PN/PF motif in the C-terminus and is paternally imprinted in placental tissue. This gene likely plays a role in placental development and spermatogenesis. [provided by RefSeq, Jan 2010]

• Gene Synonyms (homeobox protein ESX1, ESX1-related protein, extraembryonic, spermatogenesis, homeobox 1 homolog, ESX1L, ESXR1,)
• NCBI Gene ID: 80712
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8N693
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ESX homeobox 1 interacts with:

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