ASPSCR1, ASPSCR1 tether for SLC2A4, UBX domain containing

ASPSCR1, ASPSCR1 tether for SLC2A4, UBX domain containing

• The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found. [provided by RefSeq, Oct 2011]

• Gene Synonyms (tether containing UBX domain for GLUT4, ASPSCR1, UBX domain containing tether for SLC2A4, UBX domain protein 9, UBX domain-containing protein 9, alveolar soft part sarcoma chromosomal region candidate gene 1 protein, alveolar soft part sarcoma chromosome region, candidate 1, alveolar soft part sarcoma locus, renal cell carcinoma gene on chromosome 17, renal cell carcinoma, papillary, 17, renal papillary cell carcinoma protein 17, ASPCR1, ASPL, ASPS, RCC17, TUG, UBXD9, UBXN9,)
• NCBI Gene ID: 79058
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BZE9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ASPSCR1 tether for SLC2A4, UBX domain containing interacts with:

• DDB1 and CUL4 associated factor 11
  family with sequence similarity 136 member A
  inhibitor of CDK, cyclin A1 interacting protein 1
  keratin associated protein 10-8
  keratin associated protein 1-1
  notch 2 N-terminal like A
  SH3KBP1 binding protein 1
  UBX domain protein 10
  UBX domain protein 2A
  UBX domain protein 2B
  UBX domain protein 6
  valosin containing protein interacting protein 1
  valosin containing protein lysine methyltransferase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.