MUC5B, mucin 5B, oligomeric mucus/gel-forming

MUC5B, mucin 5B, oligomeric mucus/gel-forming

• This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]

• Gene Synonyms (MG1, MUC-5B, MUC5, MUC9, mucin-5B, cervical mucin MUC5B, high molecular weight salivary mucin MG1, mucin 5, subtype B, tracheobronchial, sublingual gland mucin,)
• NCBI Gene ID: 727897
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HC84
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

mucin 5B, oligomeric mucus/gel-forming interacts with:

• killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.