- Gene Overview
- Interaction Network
- Sequence Verification
BCL11B, BAF chromatin remodeling complex subunit BCL11B
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This gene encodes a C2H2-type zinc finger protein and is closely related to BCL11A, a gene whose translocation may be associated with B-cell malignancies. Although the specific function of this gene has not been determined, the encoded protein is known to be a transcriptional repressor, and is regulated by the NURD nucleosome remodeling and histone deacetylase complex. Four alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Aug 2013]
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Gene Synonyms (B-cell lymphoma/leukemia 11B, B cell CLL/lymphoma 11B, B-cell CLL/lymphoma 11B (zinc finger protein), B-cell CLL/lymphoma 11B/T-cell receptor delta constant region fusion protein, B-cell lymphoma/leukaemia 11B, BCL-11B, BCL11B, BAF complex component, BCL11B/TRDC fusion, COUP-TF-interacting protein 2, hRit1, radiation-induced tumor suppressor gene 1 protein, zinc finger protein hRit1 alpha, ATL1, ATL1-alpha, ATL1-beta, ATL1-delta, ATL1-gamma, CTIP-2, CTIP2, IDDFSTA, IMD49, RIT1, ZNF856B, hRIT1-alpha,)
- NCBI Gene ID:
64919
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>L8B862
UNIPROT ID#>>L8B8F6
UNIPROT ID#>>L8B7P7
UNIPROT ID#>>Q9C0K0
UNIPROT ID#>>L8B567
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
BAF chromatin remodeling complex subunit BCL11B interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
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