- Gene Overview
- Interaction Network
- Sequence Verification
ARAP3, ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3
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This gene encodes a phosphoinositide binding protein containing ARF-GAP, RHO-GAP, RAS-associating, and pleckstrin homology domains. The ARF-GAP and RHO-GAP domains cooperate in mediating rearrangements in the cell cytoskeleton and cell shape. It is a specific PtdIns(3,4,5)P3/PtdIns(3,4)P2-stimulated Arf6-GAP protein. An alternatively spliced transcript has been found for this gene, but its biological validity has not been determined. [provided by RefSeq, Sep 2015]
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Gene Synonyms (arf-GAP with Rho-GAP domain, ANK repeat and PH domain-containing protein 3, ARF-GAP, RHO-GAP, ankyrin repeat and plekstrin homology domains-containing protein 3, Arf and Rho GAP adapter protein 3, PtdIns(3,4,5)P3-binding protein, centaurin-delta-3, phosphoinositide binding protein, CENTD3, DRAG1,)
- NCBI Gene ID:
64411
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q05CH1
UNIPROT ID#>>Q8WWN8
UNIPROT ID#>>Q9H7C1
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
ArfGAP with RhoGAP domain, ankyrin repeat and PH domain 3 interacts with:
Paste a protein or nucleic acid sequence in the box below to confirm that it matches
this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
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