SFRP2, secreted frizzled related protein 2

SFRP2, secreted frizzled related protein 2

• This gene encodes a member of the SFRP family that contains a cysteine-rich domain homologous to the putative Wnt-binding site of Frizzled proteins. SFRPs act as soluble modulators of Wnt signaling. Methylation of this gene is a potential marker for the presence of colorectal cancer. [provided by RefSeq, Jul 2008]

• Gene Synonyms (secreted frizzled-related protein 2, SARP-1, sFRP-2, secreted apoptosis related protein 1, testicular tissue protein Li 170, FRP-2, SARP1, SDF-5,)
• NCBI Gene ID: 6423
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96HF1
  UNIPROT ID#>>B3KSM5
  UNIPROT ID#>>A0A140VJU3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

secreted frizzled related protein 2 interacts with:

• armadillo repeat containing 8
  macrophage erythroblast attacher, E3 ubiquitin ligase
  RAN binding protein 9
  required for meiotic nuclear division 5 homolog A
  secreted frizzled related protein 5
  Wnt family member 1
  Wnt family member 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.