PKNOX2, PBX/knotted 1 homeobox 2

PKNOX2, PBX/knotted 1 homeobox 2

• Homeodomain proteins are sequence-specific transcription factors that share a highly conserved DNA-binding domain and play fundamental roles in cell proliferation, differentiation, and death. PKNOX2 belongs to the TALE (3-amino acid loop extension) class of homeodomain proteins characterized by a 3-amino acid extension between alpha helices 1 and 2 within the homeodomain (Imoto et al., 2001 [PubMed 11549286]).[supplied by OMIM, Oct 2009]

• Gene Synonyms (homeobox protein PKNOX2, PBX/knotted homeobox 2, homeobox protein PREP-2, PREP2,)
• NCBI Gene ID: 63876
• Species: Homo sapiens (Human)
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

PBX/knotted 1 homeobox 2 interacts with:

• centromere protein P
  chromosome 1 open reading frame 216
  chromosome 10 open reading frame 88
  chromosome 16 open reading frame 71
  chromosome 5 open reading frame 24
  coiled-coil domain containing 116
  coiled-coil domain containing 120
  coiled-coil domain containing 185
  coiled-coil domain containing 196
  cortactin binding protein 2
  DET1 and DDB1 associated 1
  enkurin domain containing 1
  family with sequence similarity 110 member B
  myosin XVB
  PBX homeobox 4
  USH1 protein network component harmonin binding protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.