PREX1, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1

PREX1, phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1

• The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq, Jul 2008]

• Gene Synonyms (P-REX1, phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1 protein, PIP3 dependent Rac exchange factor 1, ptdIns(3,4,5)-dependent Rac exchanger 1,)
• NCBI Gene ID: 57580
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8TCU6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphatidylinositol-3,4,5-trisphosphate dependent Rac exchange factor 1 interacts with:

• RPTOR independent companion of MTOR complex 2

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