CLTRN, collectrin, amino acid transport regulator

CLTRN, collectrin, amino acid transport regulator

• This gene encodes a type 1 transmembrane protein that is important for trafficking amino acid transporters to the apical brush border of proximal tubules. The encoded protein binds to amino acid transporters and regulates their expression on the plasma membrane. It also plays a role in controlling insulin exocytosis by regulating formation of the SNARE (soluble N-ethylmaleimide-sensitive-factor attachment protein receptor) complex in pancreatic beta cells. The extracellular domain of the encoded protein may be cleaved and shed from the plasma membrane specifically in pancreatic beta cells. [provided by RefSeq, Jun 2013]

• Gene Synonyms (NX-17, NX17, TMEM27, collectrin, kidney-specific membrane protein, transmembrane protein 27,)
• NCBI Gene ID: 57393
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HBJ8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

collectrin, amino acid transport regulator interacts with:

• RNA binding motif protein 18

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.