VARS2, valyl-tRNA synthetase 2, mitochondrial

VARS2, valyl-tRNA synthetase 2, mitochondrial

• This gene encodes a mitochondrial aminoacyl-tRNA synthetase, which catalyzes the attachment of valine to tRNA(Val) for mitochondrial translation. Mutations in this gene cause combined oxidative phosphorylation deficiency-20, and are also associated with early-onset mitochondrial encephalopathies. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Aug 2014]

• Gene Synonyms (COXPD20, VALRS, VARS2L, VARSL, valine--tRNA ligase, mitochondrial, valine tRNA ligase 2, mitochondrial (putative), valyl-tRNA synthetase like,)
• NCBI Gene ID: 57176
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A1U9X9B3
  UNIPROT ID#>>Q5ST30
  UNIPROT ID#>>B4E0K6
  UNIPROT ID#>>B4DG77
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

valyl-tRNA synthetase 2, mitochondrial interacts with:

• CKLF like MARVEL transmembrane domain containing 5
  glutamate rich WD repeat containing 1
  mal, T cell differentiation protein 2
  mitochondrial rRNA methyltransferase 1
  NADH:ubiquinone oxidoreductase core subunit S7
  pleckstrin homology domain containing A4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.