PCBP4, poly(rC) binding protein 4

PCBP4, poly(rC) binding protein 4

• This gene encodes a member of the KH-domain protein subfamily. Proteins of this subfamily, also referred to as alpha-CPs, bind to RNA with a specificity for C-rich pyrimidine regions. Alpha-CPs play important roles in post-transcriptional activities and have different cellular distributions. This gene is induced by the p53 tumor suppressor, and the encoded protein can suppress cell proliferation by inducing apoptosis and cell cycle arrest in G(2)-M. This gene's protein is found in the cytoplasm, yet it lacks the nuclear localization signals found in other subfamily members. Multiple alternatively spliced transcript variants have been described, but the full-length nature for only some has been determined. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CBP, LIP4, MCG10, poly(rC)-binding protein 4, LYST-interacting protein, RNA binding protein MCG10, alpha-CP4,)
• NCBI Gene ID: 57060
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024R320
  UNIPROT ID#>>P57723
  UNIPROT ID#>>C9J0A4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

poly(rC) binding protein 4 interacts with:

• GTP binding protein 10
  tripartite motif containing 11

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