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LRRC8A, leucine rich repeat containing 8 VRAC subunit A

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LRRC8A, leucine rich repeat containing 8 VRAC subunit A

  • This gene encodes a protein belonging to the leucine-rich repeat family of proteins, which are involved in diverse biological processes, including cell adhesion, cellular trafficking, and hormone-receptor interactions. This family member is a putative four-pass transmembrane protein that plays a role in B cell development. Defects in this gene cause autosomal dominant non-Bruton type agammaglobulinemia, an immunodeficiency disease resulting from defects in B cell maturation. Multiple alternatively spliced transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]

  • Gene Synonyms (AGM5, LRRC8, SWELL1, volume-regulated anion channel subunit LRRC8A, leucine rich repeat containing 8 family member A, leucine-rich repeat-containing protein 8A, swelling protein 1,)
  • NCBI Gene ID: 56262
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q8IWT6
    UNIPROT ID#>>A0A024R892
    UNIPROT ID#>>A8K1C7
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

leucine rich repeat containing 8 VRAC subunit A interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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