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PIGV, phosphatidylinositol glycan anchor biosynthesis class V

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PIGV, phosphatidylinositol glycan anchor biosynthesis class V

  • This gene encodes a mannosyltransferase enzyme involved in the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is a complex glycolipid that functions as a membrane anchor for many proteins and plays a role in multiple cellular processes including protein sorting and signal transduction. The encoded protein is localized to the endoplasmic reticulum and transfers the second mannose to the GPI backbone. Mutations in this gene are associated with hyperphosphatasia cognitive disability syndrome. Alternatively spliced transcript variants have been observed for this gene. [provided by RefSeq, Feb 2011]

  • Gene Synonyms (GPI-MT-II, HPMRS1, PIG-V, GPI mannosyltransferase 2, GPI mannosyltransferase II, Ybr004c homolog, dol-P-Man dependent GPI mannosyltransferase,)
  • NCBI Gene ID: 55650
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q9NUD9
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

phosphatidylinositol glycan anchor biosynthesis class V interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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