NOP10, NOP10 ribonucleoprotein

NOP10, NOP10 ribonucleoprotein

• This gene is a member of the H/ACA snoRNPs (small nucleolar ribonucleoproteins) gene family. snoRNPs are involved in various aspects of rRNA processing and modification and have been classified into two families: C/D and H/ACA. The H/ACA snoRNPs also include the DKC1, NOLA1 and NOLA2 proteins. These four H/ACA snoRNP proteins localize to the dense fibrillar components of nucleoli and to coiled (Cajal) bodies in the nucleus. Both 18S rRNA production and rRNA pseudouridylation are impaired if any one of the four proteins is depleted. The four H/ACA snoRNP proteins are also components of the telomerase complex. This gene encodes a protein related to Saccharomyces cerevisiae Nop10p. [provided by RefSeq, Jul 2008]

• Gene Synonyms (DKCB1, NOLA3, NOP10P, H/ACA ribonucleoprotein complex subunit 3, NOP10 ribonucleoprotein homolog, homolog of yeast Nop10p, nucleolar protein 10, nucleolar protein family A member 3, nucleolar protein family A, member 3 (H/ACA small nucleolar RNPs), snoRNP protein NOP10,)
• NCBI Gene ID: 55505
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NPE3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NOP10 ribonucleoprotein interacts with:

• lin-28 homolog A
  lin-28 homolog B
  NHP2 ribonucleoprotein
  nuclear assembly factor 1 ribonucleoprotein
  protein phosphatase 4, catalytic subunit
  ribosome binding protein 1
  ring finger and CCCH-type domains 1
  signal recognition particle 72
  WD repeat domain 48

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.