TYW1, tRNA-yW synthesizing protein 1 homolog

TYW1, tRNA-yW synthesizing protein 1 homolog

• Wybutosine (yW) is a hypermodified guanosine found in phenylalanine tRNA adjacent to the anticodon that stabilizes codon-anticodon interactions in the ribosome. In yeast, the homolog of this gene is essential for the synthesis of wybutosine. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]

• Gene Synonyms (RSAFD1, TYW1A, YPL207W, S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase TYW1, S-adenosyl-L-methionine-dependent tRNA 4-demethylwyosine synthase, radical S-adenosyl methionine and flavodoxin domain-containing protein 1, radical S-adenosyl methionine and flavodoxin domains 1, tRNA wybutosine-synthesizing protein 1 homolog, tRNA-yW synthesizing protein 1 homolog A,)
• NCBI Gene ID: 55253
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NV66
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tRNA-yW synthesizing protein 1 homolog interacts with:

• ADAM metallopeptidase domain 33
  delta like non-canonical Notch ligand 2
  eva-1 homolog C
  G protein-coupled receptor 156
  glycerophosphodiester phosphodiesterase domain containing 5
  interleukin 17 receptor B
  interleukin 17 receptor C
  kelch like family member 40
  leucine rich repeat transmembrane neuronal 1
  MMS19 homolog, cytosolic iron-sulfur assembly component
  neuromedin U receptor 2
  protocadherin alpha 3
  protocadherin alpha subfamily C, 1
  protocadherin gamma subfamily A, 5
  ring finger protein 170
  transmembrane serine protease 3
  zinc and ring finger 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.