C1orf56, chromosome 1 open reading frame 56

C1orf56, chromosome 1 open reading frame 56

• This gene is a proto-oncogene whose promoter is methylated by DNA methyltransferase 3B (DNMT3B), which represses the proto-oncogene. However, a catalytically inactive isoform of DNMT3B is overexpressed in lymphomas, leading to hypomethylation of the proto-oncogene's promoter and derepression of the proto-oncogene. [provided by RefSeq, Sep 2016]

• Gene Synonyms (protein MENT, methylated in normal thymocytes protein, MENT,)
• NCBI Gene ID: 54964
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BUN1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

chromosome 1 open reading frame 56 interacts with:

• cytochrome c oxidase assembly factor COX20
  inhibitor of CDK, cyclin A1 interacting protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.