GEMIN8, gem nuclear organelle associated protein 8

GEMIN8, gem nuclear organelle associated protein 8

• The protein encoded by this gene is part of the SMN complex, which is necessary for spliceosomal snRNP assembly in the cytoplasm and pre-mRNA splicing in the nucleus. The encoded protein binds to both SMN1 and the GEMIN6/GEMIN7 heterodimer, mediating their interaction. This protein is found in nuclear Gemini of Cajal bodies (gems) and in the cytoplasm. Three transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, May 2010]

• Gene Synonyms (gem-associated protein 8, family with sequence similarity 51, member A1, gemin-8, FAM51A1,)
• NCBI Gene ID: 54960
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NWZ8
  UNIPROT ID#>>A0A024RBX2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

gem nuclear organelle associated protein 8 interacts with:

• gem nuclear organelle associated protein 6
  gem nuclear organelle associated protein 7
  itchy E3 ubiquitin protein ligase
  kelch like family member 8
  MMS19 homolog, cytosolic iron-sulfur assembly component
  purinergic receptor P2Y12
  SIGLEC family like 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.