FBLIM1, filamin binding LIM protein 1

FBLIM1, filamin binding LIM protein 1

• This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]

• Gene Synonyms (filamin-binding LIM protein 1, CSX-associated LIM, MIG2-interacting protein, migfilin, mitogen-inducible 2 interacting protein, CAL, FBLP-1, FBLP1,)
• NCBI Gene ID: 54751
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8WUP2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

filamin binding LIM protein 1 interacts with:

• adenosine deaminase tRNA specific 3
  chromosome 19 open reading frame 54
  H3.5 histone
  LIM domain only 3
  shisa family member 6
  tripartite motif containing 15

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.