CDK5RAP1, CDK5 regulatory subunit associated protein 1

CDK5RAP1, CDK5 regulatory subunit associated protein 1

• This gene encodes a regulator of cyclin-dependent kinase 5 activity. This protein has also been reported to modify RNA by adding a methylthio-group and may thus have a dual function as an RNA methylthiotransferase and as an inhibitor of cyclin-dependent kinase 5 activity. Alternative splicing results in multiple transcript variants that encode different isoforms. [provided by RefSeq, May 2013]

• Gene Synonyms (mitochondrial tRNA methylthiotransferase CDK5RAP1, CDK5 activator-binding protein C42, mt-tRNA-2-methylthio-N6-dimethylallyladenosine synthase, mt-tRNA-N6-(dimethylallyl)adenosine(37) methylthiotransferase, C20orf34, C42, CGI-05, HSPC167,)
• NCBI Gene ID: 51654
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0S2Z5J9
  UNIPROT ID#>>Q96SZ6
  UNIPROT ID#>>Q53H36
  UNIPROT ID#>>A0A0S2Z592
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

CDK5 regulatory subunit associated protein 1 interacts with:

• carnosine N-methyltransferase 1
  exosome component 5
  mitochondrial rRNA methyltransferase 1
  NADH:ubiquinone oxidoreductase complex assembly factor 5
  pleckstrin homology domain containing A4
  potassium channel tetramerization domain containing 17
  receptor interacting serine/threonine kinase 4
  tRNA methyltransferase 61B
  zinc finger MYND-type containing 19

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.