- Gene Overview
- Interaction Network
- Sequence Verification
DACT1, dishevelled binding antagonist of beta catenin 1
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The protein encoded by this gene belongs to the dapper family, characterized by the presence of PDZ-binding motif at the C-terminus. It interacts with, and positively regulates dishevelled-mediated signaling pathways during development. Depletion of this mRNA from xenopus embryos resulted in loss of notochord and head structures, and mice lacking this gene died shortly after birth from severe posterior malformations. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jan 2012]
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Gene Synonyms (dapper homolog 1, dapper antagonist of catenin 1, dapper, antagonist of beta-catenin, homolog 1, hepatocellular carcinoma novel gene 3 protein, heptacellular carcinoma novel gene 3, DAPPER, DAPPER1, DPR1, FRODO, HDPR1, TBS2, THYEX3,)
- NCBI Gene ID:
51339
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q9NYF0
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
cell. Learn more about other interacting partners.
dishevelled binding antagonist of beta catenin 1 interacts with:
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this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see
how a sequence matches to an experimentally-validated ORF clone.
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