ELOA2, elongin A2

ELOA2, elongin A2

• This gene encodes the transcriptionally active subunit of the SIII (or elongin) transcription elongation factor complex, which also includes two regulatory subunits, elongins B and C. This complex acts to increase the rate of RNA chain elongation by RNA polymerase II by suppressing transient pausing of the polymerase at many sites along the DNA template. Whereas a related protein with similar function, elongin A, is ubiquitously expressed, the encoded protein is specifically expressed in the testis, suggesting it may have a role in spermatogenesis. [provided by RefSeq, Jul 2008]

• Gene Synonyms (elongin-A2, RNA polymerase II transcription factor SIII subunit A2, transcription elongation factor (SIII) elongin A2 elongin A2, transcription elongation factor B polypeptide 3B, transcription elongation factor B subunit 3B, HsT832, TCEB3B, TCEB3L,)
• NCBI Gene ID: 51224
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8IYF1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

elongin A2 interacts with:

• centrosomal protein 70
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  keratin associated protein 4-12
  KxDL motif containing 1
  NKAP domain containing 1
  spermatogenesis and oogenesis specific basic helix-loop-helix 2
  SREK1 interacting protein 1
  zinc finger CCHC-type containing 10

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.