SEPSECS, Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase

SEPSECS, Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase

• The amino acid selenocysteine is the only amino acid that does not have its own tRNA synthetase. Instead, this amino acid is synthesized on its cognate tRNA in a three step process. The protein encoded by this gene catalyzes the third step in the process, the conversion of O-phosphoseryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec).[provided by RefSeq, Mar 2011]

• Gene Synonyms (O-phosphoseryl-tRNA(Sec) selenium transferase, SLA-p35, SLA/LP autoantigen, UGA suppressor tRNA-associated protein, liver-pancreas antigen, soluble liver antigen, soluble liver antigen/liver pancreas antigen, tRNA(Ser/Sec)-associated antigenic protein, LP, PCH2D, SLA, SLA/LP,)
• NCBI Gene ID: 51091
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A1A4F3
  UNIPROT ID#>>Q9HD40
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

Sep (O-phosphoserine) tRNA:Sec (selenocysteine) tRNA synthase interacts with:

• calcineurin like phosphoesterase domain containing 1
  COP1 E3 ubiquitin ligase
  deltex E3 ubiquitin ligase 2
  integrin alpha FG-GAP repeat containing 1
  leucine zipper transcription factor like 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.