PEDS1-UBE2V1, PEDS1-UBE2V1 readthrough

PEDS1-UBE2V1, PEDS1-UBE2V1 readthrough

• The TMEM189-UEV mRNA is an infrequent but naturally occurring read-through transcript of the neighboring TMEM189 and UBE2V1 genes. Ubiquitin-conjugating E2 enzyme variant proteins constitute a distinct subfamily within the E2 protein family. They have sequence similarity to other ubiquitin-conjugating enzymes but lack the conserved cysteine residue that is critical for the catalytic activity of E2s. The protein produced by this transcript has UEV1 B domains but the protein is localized to the cytoplasm rather than to the nucleus. The significance of this read-through mRNA and the function of its protein product has not yet been determined. [provided by RefSeq, Oct 2010]

• Gene Synonyms (CROC-1B, CROC1B, KUA-UEV, TMEM189-UBE2V1, TMEM189-UBE2V1 fusion protein, TMEM189-UBE2V1 readthrough transcript, transmembrane protein 189-ubiquitin-conjugating enzyme E2 variant 1 read-through,)
• NCBI Gene ID: 387522
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A5PLL7
  UNIPROT ID#>>Q13404
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

PEDS1-UBE2V1 readthrough interacts with:

• G protein-coupled receptor 152
  NME1-NME2 readthrough

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