SUMO4, small ubiquitin like modifier 4

SUMO4, small ubiquitin like modifier 4

• This gene is a member of the SUMO gene family. This family of genes encode small ubiquitin-related modifiers that are attached to proteins and control the target proteins' subcellular localization, stability, or activity. The protein described in this record is located in the cytoplasm and specifically modifies IKBA, leading to negative regulation of NF-kappa-B-dependent transcription of the IL12B gene. A specific polymorphism in this SUMO gene, which leads to the M55V substitution, has been associated with type I diabetes. The RefSeq contains this polymorphism. [provided by RefSeq, Jul 2008]

• Gene Synonyms (IDDM5, SMT3H4, SUMO-4, dJ281H8.4, small ubiquitin-related modifier 4, SMT3 suppressor of mif two 3 homolog 2, SMT3 suppressor of mif two 3 homolog 4, insulin-dependent diabetes mellitus 5, small ubiquitin-like modifier 4 protein,)
• NCBI Gene ID: 387082
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q6EEV6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

small ubiquitin like modifier 4 interacts with:

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