- Gene Overview
- Interaction Network
- Sequence Verification
CTAG2, cancer/testis antigen 2
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This gene encodes an autoimmunogenic tumor antigen that belongs to the ESO/LAGE family of cancer-testis antigens. This protein is expressed in a wide array of cancers including melanoma, breast cancer, bladder cancer and prostate cancer. This protein is also expressed in normal testis tissue. An alternative open reading frame product of this gene has been described in PMID:10399963. This alternate protein, termed CAMEL, is a tumor antigen that is recognized by melanoma-specific cytotoxic T-lymphocytes. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013]
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Gene Synonyms (cancer/testis antigen 2, CTL-recognized antigen on melanoma, LAGE-1a protein, autoimmunogenic cancer/testis antigen NY-ESO-2, cancer/testis antigen 6.2, cancer/testis antigen family 6, member 2a, cancer/testis antigen family 6, member 2b, l antigen family member 1, CAMEL, CT2, CT6.2, CT6.2a, CT6.2b, ESO2, LAGE-1, LAGE2B,)
- NCBI Gene ID:
30848
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>O75638
- View the NCBI Database
for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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cancer/testis antigen 2 interacts with:
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