NXT1, nuclear transport factor 2 like export factor 1

NXT1, nuclear transport factor 2 like export factor 1

• The protein encoded by this gene is located in the nuclear envelope. It has protein similarity to nuclear transport factor 2. This protein functions as a nuclear export factor in both RAN (Ras-related nuclear protein)- and CRM1 (required for chromosome region maintenance)-dependent pathways. It is found to stimulate the export of U1 snRNA in RAN- and CRM1-dependent pathways and the export of tRNA and mRNA in a CRM1-independent pathway. The encoded protein heterodimerizes with Tap protein and may regulate the ability of Tap protein to mediate nuclear mRNA export. The use of alternate polyadenylation sites has been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (NTF2-related export protein 1, NTF2-like export factor 1, NTX2-like export factor1, NUTF-like export factor 1, protein p15, MTR2, P15,)
• NCBI Gene ID: 29107
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UKK6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear transport factor 2 like export factor 1 interacts with:

• F-box protein 16
  nuclear RNA export factor 2
  nuclear RNA export factor 3
  nucleoporin 107
  nucleoporin 98
  vacuolar protein sorting 36 homolog

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.