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DPH3, diphthamide biosynthesis 3

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DPH3, diphthamide biosynthesis 3

  • This gene encodes a CSL zinc finger-containing protein that is required for dipthamide biosynthesis. The encoded protein is necessary for the initial step in the modification of a histidine residue in elongation factor-2 to diphthamide. This modified residue is a target for ADP ribosylation by the bacterial toxins diphtheria toxin and Pseudomonas exotoxin A. Alternative splicing results in multiple transcript variants that encode the same isoform. [provided by RefSeq, Feb 2009]

  • Gene Synonyms (DPH3 homolog, CSL-type zinc finger-containing protein 2, DPH3 homolog (KTI11, S. cerevisiae), DPH3, KTI11 homolog, DPH3A, KTI11 homolog A, Del-GEF interacting protein, deafness locus putative guanine nucleotide exchange factor interacting protein 1, delGEF-interacting protein 1, diphtheria toxin and Pseudomonas exotoxin A sensitivity required gene 1, zinc finger, CSL domain containing 2, zinc finger, CSL-type containing 2, DELGIP, DELGIP1, DESR1, DPH3A, KTI11, ZCSL2,)
  • NCBI Gene ID: 285381
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>A0A024R2P5
    UNIPROT ID#>>Q96FX2
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

diphthamide biosynthesis 3 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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