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FBXW12, F-box and WD repeat domain containing 12

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FBXW12, F-box and WD repeat domain containing 12

  • Members of the F-box protein family, such as FBXW12, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603034), and F-box proteins, act as protein-ubiquitin ligases. F-box proteins interact with SKP1 through the F box, and they interact with ubiquitination targets through other protein interaction domains (Jin et al., 2004 [PubMed 15520277]).[supplied by OMIM, Mar 2008]

  • Gene Synonyms (F-box/WD repeat-containing protein 12, F-box and WD-40 domain protein 12, F-box and WD-40 domain-containing protein 12, F-box only protein 35, F-box- and WD40-repeat-containing protein, FBW12, FBXO12, FBXO35,)
  • NCBI Gene ID: 285231
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q6X9E4
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

F-box and WD repeat domain containing 12 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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