WFDC10B, WAP four-disulfide core domain 10B

WFDC10B, WAP four-disulfide core domain 10B

• This gene encodes a member of the WAP-type four-disulfide core (WFDC) domain family. The WFDC domain, or WAP signature motif, contains eight cysteines forming four disulfide bonds at the core of the protein, and functions as a protease inhibitor. Most WFDC gene members are localized to chromosome 20q12-q13 in two clusters: centromeric and telomeric. This gene belongs to the telomeric cluster. Two alternatively spliced transcript variants have been found for this gene, and they encode distinct isoforms. [provided by RefSeq, Jul 2008]

• Gene Synonyms (protein WFDC10B, protease inhibitor WAP12, WAP12,)
• NCBI Gene ID: 280664
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8IUB3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

WAP four-disulfide core domain 10B interacts with:

• keratin associated protein 10-3

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