Vkorc1, vitamin K epoxide reductase complex, subunit 1

Vkorc1, vitamin K epoxide reductase complex, subunit 1

• Vitamin K is essential for blood clotting but must be enzymatically activated. This enzymatically activated form of vitamin K is a reduced form required for the carboxylation of glutamic acid residues in some blood-clotting proteins. The product of this gene encodes the enzyme that is responsible for reducing vitamin K 2,3-epoxide to the enzymatically activated form. Fatal bleeding can be caused by vitamin K deficiency and by the vitamin K antagonist warfarin, and it is the product of this gene that is sensitive to warfarin. In humans, mutations in this gene can be associated with deficiencies in vitamin-K-dependent clotting factors and, in humans and rats, with warfarin resistance. [provided by RefSeq, Jul 2008]

• (No alternate names found)
• NCBI Gene ID: 27973
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>Q9CRC0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

vitamin K epoxide reductase complex, subunit 1 interacts with:

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