ANGPTL3, angiopoietin like 3

ANGPTL3, angiopoietin like 3

• This gene encodes a member of a family of secreted proteins that function in angiogenesis. The encoded protein, which is expressed predominantly in the liver, is further processed into an N-terminal coiled-coil domain-containing chain and a C-terminal fibrinogen chain. The N-terminal chain is important for lipid metabolism, while the C-terminal chain may be involved in angiogenesis. Mutations in this gene cause familial hypobetalipoproteinemia type 2. [provided by RefSeq, Aug 2015]

• Gene Synonyms (angiopoietin-related protein 3, angiopoietin 5, ANG-5, ANGPT5, ANL3, FHBL2,)
• NCBI Gene ID: 27329
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9Y5C1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

angiopoietin like 3 interacts with:

• baculoviral IAP repeat containing 6
  coiled-coil domain containing 91
  GULP PTB domain containing engulfment adaptor 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.