VPS41, VPS41 subunit of HOPS complex

VPS41, VPS41 subunit of HOPS complex

• Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene encodes the human ortholog of yeast Vps41 protein which is also conserved in Drosophila, tomato, and Arabidopsis. Expression studies in yeast and human indicate that this protein may be involved in the formation and fusion of transport vesicles from the Golgi. Several transcript variants encoding different isoforms have been described for this gene, however, the full-length nature of not all is known. [provided by RefSeq, Jul 2008]

• Gene Synonyms (HVPS41, HVSP41, hVps41p, vacuolar protein sorting-associated protein 41 homolog, S53, VPS41, HOPS complex subunit, vacuolar assembly protein 41, vacuolar protein sorting 41 homolog,)
• NCBI Gene ID: 27072
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P49754
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

VPS41 subunit of HOPS complex interacts with:

• ADP ribosylation factor like GTPase 8B
  AKT interacting protein
  cancer/testis antigen 55
  hook microtubule tethering protein 1
  hook microtubule tethering protein 2
  hook microtubule tethering protein 3
  nucleic acid binding protein 2
  protein prenyltransferase alpha subunit repeat containing 1
  Rab interacting lysosomal protein
  syntaxin 17
  transcription elongation factor A like 4
  ubiquitin conjugating enzyme E2 U
  UTP20 small subunit processome component
  VPS11 core subunit of CORVET and HOPS complexes
  VPS16 core subunit of CORVET and HOPS complexes
  VPS18 core subunit of CORVET and HOPS complexes
  VPS33A core subunit of CORVET and HOPS complexes
  VPS33B interacting protein, apical-basolateral polarity regulator, spe-39 homolog
  zinc finger containing ubiquitin peptidase 1
  zinc finger protein 512B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.