SHPK, sedoheptulokinase

SHPK, sedoheptulokinase

• The protein encoded by this gene has weak homology to several carbohydrate kinases, a class of proteins involved in the phosphorylation of sugars as they enter a cell, inhibiting return across the cell membrane. Sequence variation between this novel gene and known carbohydrate kinases suggests the possibility of a different substrate, cofactor or changes in kinetic properties distinguishing it from other carbohydrate kinases. The gene resides in a region commonly deleted in cystinosis patients, suggesting a role as a modifier for the cystinosis phenotype. The genomic region is also rich in Alu repetitive sequences, frequently involved in chromosomal rearrangements. [provided by RefSeq, Jul 2008]

• Gene Synonyms (sedoheptulokinase, carbohydrate kinase-like protein, CARKL, SHK,)
• NCBI Gene ID: 23729
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UHJ6
  UNIPROT ID#>>A0A0B4J2A0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sedoheptulokinase interacts with:

• ADP ribosylation factor GTPase activating protein 3
  EP300 interacting inhibitor of differentiation 2B
  family with sequence similarity 126 member A
  family with sequence similarity 219 member A
  glutamine amidotransferase like class 1 domain containing 1
  thymocyte nuclear protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.