TRAM1, translocation associated membrane protein 1

TRAM1, translocation associated membrane protein 1

• This gene encodes a multi-pass membrane protein that is part of the mammalian endoplasmic reticulum. The encoded protein influences glycosylation and facilitates the translocation of secretory proteins across the endoplasmic reticulum membrane by regulating which domains of the nascent polypeptide chain are visible to the cytosol during a translocational pause. [provided by RefSeq, Oct 2009]

• Gene Synonyms (translocating chain-associated membrane protein 1, translocating chain-associating membrane protein, translocation-associating membrane protein 1, PNAS8, TRAM, TRAMP,)
• NCBI Gene ID: 23471
• Species: Homo sapiens (Human)
• UNIPROT ID#>>G3XAN4
  UNIPROT ID#>>Q6FHL3
  UNIPROT ID#>>Q15629
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

translocation associated membrane protein 1 interacts with:

• derlin 1
  HCLS1 associated X-1
  histocompatibility minor 13
  membrane bound O-acyltransferase domain containing 1
  OTU deubiquitinase with linear linkage specificity like
  pleckstrin homology domain containing A4
  potassium channel tetramerisation domain containing 5
  solute carrier family 15 member 3
  tectonic family member 3
  TIR domain containing adaptor protein
  toll like receptor adaptor molecule 1
  unc-93 homolog B1, TLR signaling regulator
  vitamin K epoxide reductase complex subunit 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.