DDHD2, DDHD domain containing 2

DDHD2, DDHD domain containing 2

• This gene encodes a phospholipase enzyme containing sterile-alpha-motif (SAM), WWE, and DDHD domains. This protein participates in membrane trafficking between the endoplastic reticulum and the Golgi body. Mutations in this gene can cause autosomal recessive spastic paraplegia 54. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

• Gene Synonyms (SAMWD1, SPG54, iPLA(1)gamma, phospholipase DDHD2, PA-PLA1 like, SAM, WWE and DDHD domain-containing protein 1, intracellular phospholipase A1gamma, sec23p-interacting protein p125-like phosphatidic acid-preferring phospholipase A1,)
• NCBI Gene ID: 23259
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B3KPM6
  UNIPROT ID#>>O94830
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

DDHD domain containing 2 interacts with:

• alanyl-tRNA synthetase domain containing 1
  chromosome 2 open reading frame 68
  leucine rich repeat containing 8 VRAC subunit E
  RCC1 domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.